
产品货号:
Z14281
中文名称:
COPS7B抗体
英文名称:
Anti-COPS7B Antibody (N-Term)
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-COPS7B Antibody (N-Term) |
指标别名 | COP9 signalosome complex subunit 7b;SGN7b;Signalosome subunit 7b;JAB1-containing signalosome subunit 7b;COPS7B;CSN7B |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM,IHC |
基因名称 | COPS7B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This COPS7B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 61-95 amino acids from human COPS7B. |
计算分子量 | 30kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Component of the COP9 signalosome complex (CSN),a complex involved in various cellular and developmental processes.The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes,leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF,CSA or DDB2.The complex is also involved in phosphorylation of p53/TP53,JUN,I-kappa-B-alpha/NFKBIA,ITPK1 and IRF8/ICSBP,possibly via its association with CK2 and PKD kinases.CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system,respectively. |
Uniprot ID | Q9H9Q2 |
相关搜索:COPS7B抗体,COPS7B(N-Term)多抗,Anti-COPS7B Antibody (N-Term)